Metallic germicidal solution and method of making same



- hence, a stronger concentration is more Patented 7,

zssaszs uN-lrsofls'ra'rssi- PATENT OFFICE METALLIC GERHICIDAL AND METHOD West Los Angeles, and Howard Calif Anthony J. Salle,

L. Guest. Ocean half a Leo a. Gunther mtm'cuu.

No small mum 0mm a ar NoJOSMl of one- Claims. (Cl. 187-14) Heretofcre, mercury compounds and solutions of metallic compounds of iodine inthe oaidised form have been employed as germicides and antiseptics. Such mercury and iodine solutions,

when, applied to body tissue for killing micro organisms such, for example, as Staphylococcus aureus, and must be used in concentrations that are destructive to such tissue if strong enough to be elective for killing the micro-organismm The mercury solutions have been particularly destructive to tissue. Manifestly, the cost of the solutions is dependent pon the concentration: costly than a weaker one, but heretofore dilution solution to the point where its causticity to tissue is substantially non-existent has resulted corresponding decrease in itsgermicidal proper ties.

By this invention such'germicidal solutions as above ment oped-may be diluted to a point where it issubstantially non-caustic to body tissue while Also, by this invention, an effective, stainless germicide is produced from stannlc chloride ina solution that is non-cau'stic'to tissue,

Objects ofthis invention are the production of germicidal solutions from metallic compounds in an oxidized formthat have heretofore been obiectionably' irritating, and caustic to body tissue,

economic germicide without loss as compared with standard solu- Staphylococcus aurcus, since this is commonly used for tests, and most prevalent in wounds.

Briefly described, to each one gram molecular weight of the mercury compound, tin compound or metallic compound of iodine in the oxidized form, such as mercuric chloride, stannic chloride,

or any metallic compound of iodine, we add one equivalent weight of a reducing agent such-as ferrous sulphate, ferrous chloride, stannous chloride, manganous chloride, or manganous sulphate. Any reducing agent which is soluble in the end product, and which will not precipitate coccus mucus, is 1:18000 and its effective germicidal concentration is 123000 but the destructive effect of such a solution to body tissue is obiectionablef however, by the addition of the reducofa former. V

the eii'ective dilution is ing agent as described, the least lethal dilution becomes 1:40000 and the eii'ective germicidal dilutlon 1:8000 which is considerably less toxic to tissue than the greater concentration of the Before the addition of the reducing agent to stannic chloride, the least lethal dilution is 1:50 and an effective dilution would be 1:10, which dilution is very'irritating andobiectionably destructive to tissue; however, by adding the reduc-. ing agent, the least lethal dilution is 1:150 and 1 :50 which is correspondingly less irritating.

The metallic compound of iodine with the addition of the reducing agent has its killing power proportionally increased about three times, thus enabling its dilution to the point where it is less destructive to tissue, but is still as germicidal as the greater and more caustic concentration beretaining ,the desired germicidal properties. i

. from the ferrous chloride, stannous chloride, manganous or be precipitated by the compound, is suitable. Before the addition of a reducing agent, such a as oneof the above, the least lethal dilution of mercuric chloride in ten minutes, to Stumbthe fore the addition of the reducing agent and water.

In view of the cheapness of the reducing agents used and the increased effectiveness of the solutions as germicides, it is seen that the higher dilutions to obtain the equivalent killing power of the prior caustic solutions results in a much cheaper product, eral are stainless as also are the tin salts.

Having described our invention, we claim:

1. The method of increasing the germicidal property of a solution of one of the group consisting of mercuric chloride andstannic chloride, that comprises the step of adding to each gram molecular weight of such metallic compound an equivalent weight of a reducing agent from the group consisting of ferrous sulphate, ferrous chloride, stannous chloride, manganous chloride and manganous sulfate.

'2. A germicidal product for use in a solution that comprises a'metallic compound from the "group consisting of mercuric chloride and stannic chloride, to each molecular weight of which is added an equivalent weight of a reducing agent group consisting of ferrous sulfate,

chloride and manganous sulfate.

3. A stimicidal aqueous solution containing I one of the group consisting of'mercuric chloride and stannlc chloride, and a reducing agent from of ferrous sulfate, ferrous group consisting chloride, stannous chloride, manganous chloride,

and the mercury salts in genand manganous sulfate, in the proportion of a gram molecular weight 01- the reducing agent to each gram molecular weight of the metallic compoun 4. substantially stainless germicidal solution containing one of the group consisting of mercuric chloride and stannic chloride and an equivalent weight of stannous chloride to each gram molecular weight of the mercuric chloride or stannlc chloride.

5..-A solution having a germicidal property,.-

when applied to Staphylococcus 4min, substantiiilll equal to a 1:50 solution of stannic chloride that comprises substantially 1:150 solution of 'stannic chloride and a reducing agent from the group consisting oi ferrous sulfate, ferrous chloride, stannous chloride, manganous chloride and manganous sulfate, the amoimt oi saidreducing agent in'said solution being one gram molecular weight for each Jlflm molecular weight oi. the mercuricohloride.

ANTHONY J. sum.

HOWARD L. GUEST. 

